STAT4 gene polymorphism in patients after renal allograft transplantation

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STAT4 gene polymorphism in patients after renal allograft transplantation

INTRODUCTION STAT4 (signal transducer and activator of transcription 4) is involved in the regulation of innate and adaptive immune responses. Some studies have suggested that STAT4 may be involved in the immune response after graft transplantation. Several polymorphisms in the STAT4 gene have been identified. The most commonly studied polymorphism in the STAT4 gene is rs7574865. In our study, ...

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Renalase gene polymorphism in patients after renal allograft transplantation.

BACKGROUND/AIMS Renalase is a recently discovered protein, which is likely involved in regulation of blood pressure in humans and animals. Previous studies suggest that renalase reflects kidney functioning. A common missense polymorphism in the flavin-adenine dinucleotide-binding domain of human renalase (Glu37Asp) has been described. In this study we examined the association between (Glu37Asp)...

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Seizure disorders after renal Transplantation in children

Background and Objective: Some neurologic complications may be detected after renal transplantation in children including tremor, peripheral neuropathy, altered level of consciousness and seizure. The aim of our study was to detect the prevalence of seizure after renal transplantation and its risk factors in pediatric age groups. Methods: In this descriptive study, 102 patients 5-14 yea...

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FcγRIIa defunctioning polymorphism in paediatric patients with renal allograft

Introduction Fc gamma receptor (FcγR) IIa is considered the most widely distributed of the three classes of Fc receptors, and it expresses an allelic polymorphism. This type of polymorphism may modify the immune response and may be an important factor for some diseases. The aim of the study reported herein was to evaluate the association between the FcγRIIa polymorphism and susceptibility to bo...

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Spontaneous renal allograft rupture 4 years after transplantation.

Previously, the longest reported interval between clinical renal transplantation and 'spontaneous' renal allograft rupture was 170 days. We here report a case with an interval of 4 years between renal transplantation and the delayed 'spontaneous' renal allograft rupture (DSR). The aetiology appears to be a vigorous rejection confirmed by operative and pathological findings. The patient who was ...

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ژورنال

عنوان ژورنال: Central European Journal of Immunology

سال: 2016

ISSN: 1426-3912

DOI: 10.5114/ceji.2016.63124